Mouse Sox17 activation kit by CRISPRa

CAT#: GA204032

Sox17 CRISPRa kit - CRISPR gene activation of mouse SRY (sex determining region Y)-box 17

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sox17
• Locus ID: 20671
• Kit Components:

  GA204032G1, Sox17 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204032G2, Sox17 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204032G3, Sox17 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289464, NM_001289465, NM_001289466, NM_001289467, NM_011441
• Summary: This gene encodes a member of the Sox (Sry-related high mobility group box) family of transcription factors involved in the regulation of embryonic development. The encoded protein plays a role in the determination of cell fate and in maintaining cell identity. This gene regulates tumor angiogenesis and tumor progression. Mutations in the human gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]