Mouse Srp14 activation kit by CRISPRa

CAT#: GA204107

Srp14 CRISPRa kit - CRISPR gene activation of mouse signal recognition particle 14

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Srp14
• Locus ID: 20813
• Kit Components:

  GA204107G1, Srp14 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204107G2, Srp14 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204107G3, Srp14 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_009273
• Synonyms: 14kDa; AW536328
• Summary: Signal-recognition-particle assembly has a crucial role in targeting secretory proteins to the rough endoplasmic reticulum membrane. SRP9 together with SRP14 and the Alu portion of the SRP RNA, constitutes the elongation arrest domain of SRP. The complex of SRP9 and SRP14 is required for SRP RNA binding. [UniProtKB/Swiss-Prot Function]