Mouse Plk4 activation kit by CRISPRa

CAT#: GA204142

Plk4 CRISPRa kit - CRISPR gene activation of mouse polo like kinase 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Plk4
• Locus ID: 20873
• Kit Components:

  GA204142G1, Plk4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204142G2, Plk4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204142G3, Plk4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_011495, NM_173169, NR_045576
• Synonyms: 1700028H20; AI385771; Sak; Stk18
• Summary: This gene encodes a member of the polo family of serine/threonine protein kinases. The protein localizes to the nucleolus during G2, to centrosomes during G2/M, and to the cleavage furrow during cytokinesis. It is required for progression through mitosis, cell survival, and embryonic development. The mouse genome contains a pseudogene similar to this gene. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]