Mouse Prdx2 activation kit by CRISPRa

CAT#: GA204278

Prdx2 CRISPRa kit - CRISPR gene activation of mouse peroxiredoxin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Prdx2
• Locus ID: 21672
• Kit Components:

  GA204278G1, Prdx2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204278G2, Prdx2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204278G3, Prdx2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317385, NM_011563
• Synonyms: AL022839; Band-8; NkefB; PRP; PrxII; Tdpx1; TDX1; Torin; TPx; TPx-B; TR; TSA
• Summary: Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2). [UniProtKB/Swiss-Prot Function]