Mouse Tead4 activation kit by CRISPRa

CAT#: GA204283

Tead4 CRISPRa kit - CRISPR gene activation of mouse TEA domain family member 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Tead4
• Locus ID: 21679
• Kit Components:

  GA204283G1, Tead4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204283G2, Tead4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204283G3, Tead4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001080979, NM_011567
• Synonyms: ETFR-2; Etfr2; FR-19; Rtef1; Tcf13r1; TEAD-4; TEF-3; Tef3; Tefr; Tefr1; Tefr1a
• Summary: This gene product is a member of the transcriptional enhancer factor (TEF) family of transcription factors, which contain the TEA/ATTS DNA-binding domain. It is preferentially expressed in the skeletal muscle, and binds to the M-CAT regulatory element found in promoters of muscle-specific genes to direct their gene expression. This factor may play a role in the embryonic development of skeletal muscle. Alternatively spliced transcripts encoding distinct isoforms, which are translated through the use of a non-AUG (AUU) initiation codon, have been described for this gene. [provided by RefSeq, Jul 2008]