Mouse Terf1 activation kit by CRISPRa

CAT#: GA204294

Terf1 CRISPRa kit - CRISPR gene activation of mouse telomeric repeat binding factor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Terf1
• Locus ID: 21749
• Kit Components:

  GA204294G1, Terf1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204294G2, Terf1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204294G3, Terf1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001286628, NM_009352, NR_152944
• Synonyms: Pin2; Trbf1; Trf1
• Summary: This gene encodes a protein that binds to repeats in telomeres to form a nucleoprotein complex that protects against the degradation of chromosomal ends. The encoded protein regulates the length of telomeres and is an integral structural component of the functional telomere. This protein is thought to play a role in spindle formation in mitosis. Mutations in this gene are associated with bone marrow failure. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Nov 2013]