Mouse Tgfa activation kit by CRISPRa
CAT#: GA204316
Tgfa CRISPRa kit - CRISPR gene activation of mouse transforming growth factor alpha
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Tgfa |
Locus ID | 21802 |
Kit Components | GA204316G1, Tgfa gRNA vector 1 in pCas-Guide-CRISPRa GA204316G2, Tgfa gRNA vector 2 in pCas-Guide-CRISPRa GA204316G3, Tgfa gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_031199 |
Synonyms | wa-1; wa1 |
Summary | This gene encodes a member of the epidermal growth factor (EGF) family of proteins that regulate cellular proliferation. The encoded protein undergoes proteolytic processing to generate a soluble glycoprotein that is secreted by the cell. The secreted protein binds to the EGF receptors to initiate signaling events resulting in cellular proliferation, mucous production or inhibition of gastric acid secretion. The transgenic expression of the encoded protein in mice induces the development of cancers in various tissues such as liver, pancreas, skin and mammary glands. Mice lacking the encoded protein exhibit a wavy coat and curly whiskers phenotype as well as abnormalities in the eye. [provided by RefSeq, Sep 2015] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN517481 | Tgfa - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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