Mouse Thbs1 activation kit by CRISPRa

CAT#: GA204334

Thbs1 CRISPRa kit - CRISPR gene activation of mouse thrombospondin 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Thbs1
• Locus ID: 21825
• Kit Components:

  GA204334G1, Thbs1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204334G2, Thbs1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204334G3, Thbs1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313914, NM_011580
• Synonyms: tbsp1; Thbs-1; TSP-1; TSP1
• Summary: The protein encoded by this gene is a subunit of a disulfide-linked homotrimeric protein. This protein is an adhesive glycoprotein that mediates cell-to-cell and cell-to-matrix interactions. This protein can bind to fibrinogen, fibronectin, laminin, type V collagen and integrins alpha-V/beta-1. This protein has been shown to play roles in platelet aggregation, angiogenesis, and tumorigenesis. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2015]