Mouse Thra activation kit by CRISPRa

CAT#: GA204340

Thra CRISPRa kit - CRISPR gene activation of mouse thyroid hormone receptor alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Thra
• Locus ID: 21833
• Kit Components:

  GA204340G1, Thra gRNA vector 1 in pCas-Guide-CRISPRa

  GA204340G2, Thra gRNA vector 2 in pCas-Guide-CRISPRa

  GA204340G3, Thra gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001313983, NM_178060
• Synonyms: 6430529J03Rik; AW259572; c-erbA-1; c-erbA-alpha; c-erbAalpha; Erba; Nr1a1; Rvr; T3Ralpha
• Summary: The protein encoded by this gene is one of several nuclear hormone receptors that bind thyroid hormones such as triiodothyronine and thyroxine with high affinity. The encoded protein is a transcription factor that can activate or repress transcription. Several alternatively spliced transcript variants of this gene have been described, but the full-length nature of some of these variants has not been determined. [provided by RefSeq, Sep 2015]