Mouse Ucn activation kit by CRISPRa

CAT#: GA204529

Ucn CRISPRa kit - CRISPR gene activation of mouse urocortin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ucn
• Locus ID: 22226
• Kit Components:

  GA204529G1, Ucn gRNA vector 1 in pCas-Guide-CRISPRa

  GA204529G2, Ucn gRNA vector 2 in pCas-Guide-CRISPRa

  GA204529G3, Ucn gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001346010, NM_021290
• Synonyms: Mpv17; Ucn1
• Summary: This gene encodes a member of the corticotropin-releasing hormone peptide family that participates in coordinating autonomic, endocrine, and behavioral responses to stress. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone. Mice lacking the encoded protein exhibit a heightened anxiety-like behaviors and a significantly reduced acoustic startle response. [provided by RefSeq, Sep 2016]