Mouse Xdh activation kit by CRISPRa

CAT#: GA204650

Xdh CRISPRa kit - CRISPR gene activation of mouse xanthine dehydrogenase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Xdh
• Locus ID: 22436
• Kit Components:

  GA204650G1, Xdh gRNA vector 1 in pCas-Guide-CRISPRa

  GA204650G2, Xdh gRNA vector 2 in pCas-Guide-CRISPRa

  GA204650G3, Xdh gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_011723
• Synonyms: XO; Xor; Xox-1; Xox1
• Summary: This gene encodes a member of the xanthine dehydrogenase protein family. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. The encoded protein exists as two distinct enzymatic forms, either as xanthine dehydrogenase, or as xanthine oxidase, and functions in purine degradation. Additional studies also suggest a role in adipogenesis, and a function as a structural protein in milk fat droplets in the lactating mammary gland. [provided by RefSeq, Jan 2014]