Mouse Mpdu1 activation kit by CRISPRa

CAT#: GA204888

Mpdu1 CRISPRa kit - CRISPR gene activation of mouse mannose-P-dolichol utilization defect 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Mpdu1
• Locus ID: 24070
• Kit Components:

  GA204888G1, Mpdu1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204888G2, Mpdu1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204888G3, Mpdu1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301710, NM_001301711, NM_011900, NR_125917
• Synonyms: LEC35; SL15; Supl15h
• Summary: This gene encodes a member of the PQ-loop superfamily. A similar gene in human encodes a protein that is required for monosaccharide-P-dolichol-dependent glycosyltransferase reactions, and disruption of this gene is the cause of congenital disorder of glycosylation (CDG) type 1F, a disease linked to defects in protein N-glycosylation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2014]