Mouse Uts2 activation kit by CRISPRa

CAT#: GA204904

Uts2 CRISPRa kit - CRISPR gene activation of mouse urotensin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Uts2
• Locus ID: 24111
• Kit Components:

  GA204904G1, Uts2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204904G2, Uts2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204904G3, Uts2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_011910
• Synonyms: prepro-UII; Ucn2; UII
• Summary: This gene encodes a member of the urotensin family of peptide hormones. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional hormone before secretion into the plasma. Mice lacking the encoded protein have a significantly decreased low density lipoprotein cholesterol profile and hepatic steatosis that is consistent with decreased hepatocyte de novo cholesterol synthesis and apolipoprotein B secretion. [provided by RefSeq, Sep 2016]