Mouse Abcg2 activation kit by CRISPRa

CAT#: GA204916

Abcg2 CRISPRa kit - CRISPR gene activation of mouse ATP binding cassette subfamily G member 2 (Junior blood group)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Abcg2
• Locus ID: 26357
• Kit Components:

  GA204916G1, Abcg2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA204916G2, Abcg2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA204916G3, Abcg2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_011920, NM_001355477
• Synonyms: ABC15; ABCP; AI428558; BCRP; Bcrp1; MXR; MXR1
• Summary: The membrane-associated protein encoded by this gene is included in the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. Alternatively referred to as a breast cancer resistance protein, the human protein functions as a xenobiotic transporter which may play a major role in multi-drug resistance. This protein likely serves as a cellular defense mechanism in response to mitoxantrone and anthracycline exposure. [provided by RefSeq, Jul 2008]