Mouse Cartpt activation kit by CRISPRa

CAT#: GA205104

Cartpt CRISPRa kit - CRISPR gene activation of mouse CART prepropeptide

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cartpt
• Locus ID: 27220
• Kit Components:

  GA205104G1, Cartpt gRNA vector 1 in pCas-Guide-CRISPRa

  GA205104G2, Cartpt gRNA vector 2 in pCas-Guide-CRISPRa

  GA205104G3, Cartpt gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001081493, NM_013732
• Synonyms: Cart
• Summary: This gene encodes preproprotein isoforms that are processed into multiple biologically active peptides. Expression of this gene is regulated by cocaine and other drugs, and is associated with feeding/appetite and stress response. Mice lacking the encoded protein are predisposed to obesity. Deficiency of the encoded protein in mice results in pancreatic islet dysfunction, impaired insulin secretion and glucose intolerance. Alternative splicing results in multiple transcript variants encoding different isoforms, which are subsequently processed into mature peptides. [provided by RefSeq, Jul 2015]