Mouse Il27ra activation kit by CRISPRa

CAT#: GA205405

Il27ra CRISPRa kit - CRISPR gene activation of mouse interleukin 27 receptor, alpha

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Il27ra
• Locus ID: 50931
• Kit Components:

  GA205405G1, Il27ra gRNA vector 1 in pCas-Guide-CRISPRa

  GA205405G2, Il27ra gRNA vector 2 in pCas-Guide-CRISPRa

  GA205405G3, Il27ra gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_016671
• Synonyms: CRL1; IL-27R; Tccr; WSX-1; Wsx1; zcytor1
• Summary: Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms. [UniProtKB/Swiss-Prot Function]