Mouse Dnmt3l activation kit by CRISPRa

CAT#: GA205712

Dnmt3l CRISPRa kit - CRISPR gene activation of mouse DNA (cytosine-5-)-methyltransferase 3-like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dnmt3l
• Locus ID: 54427
• Kit Components:

  GA205712G1, Dnmt3l gRNA vector 1 in pCas-Guide-CRISPRa

  GA205712G2, Dnmt3l gRNA vector 2 in pCas-Guide-CRISPRa

  GA205712G3, Dnmt3l gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001081695, NM_001284197, NM_001284198, NM_001284199, NM_001284200, NM_019448
• Synonyms: D6Ertd14e; ecat7
• Summary: CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a nuclear protein that is a catalytically inactive regulatory factor of DNA methyltransferases. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Sep 2015]