Mouse Sfrp5 activation kit by CRISPRa

CAT#: GA205736

Sfrp5 CRISPRa kit - CRISPR gene activation of mouse secreted frizzled-related sequence protein 5

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Sfrp5
• Locus ID: 54612
• Kit Components:

  GA205736G1, Sfrp5 gRNA vector 1 in pCas-Guide-CRISPRa

  GA205736G2, Sfrp5 gRNA vector 2 in pCas-Guide-CRISPRa

  GA205736G3, Sfrp5 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_018780
• Synonyms: AI605071; SARP3
• Summary: Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP5 may be involved in determining the polarity of photoreceptor, and perhaps, other cells in the retina. [UniProtKB/Swiss-Prot Function]