Mouse Cldn14 activation kit by CRISPRa

CAT#: GA205842

Cldn14 CRISPRa kit - CRISPR gene activation of mouse claudin 14

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cldn14
• Locus ID: 56173
• Kit Components:

  GA205842G1, Cldn14 gRNA vector 1 in pCas-Guide-CRISPRa

  GA205842G2, Cldn14 gRNA vector 2 in pCas-Guide-CRISPRa

  GA205842G3, Cldn14 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001165925, NM_001165926, NM_019500
• Synonyms: AI851731
• Summary: This gene encodes a member of the claudin family of tight junction proteins. The encoded protein is an integral membrane protein that may function in maintaining apical membrane polarization in tight junctions located between outer hair cells and supporting cells. Loss of function of this gene is associated with hearing problems. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]