Mouse Fxyd1 activation kit by CRISPRa

CAT#: GA205849

Fxyd1 CRISPRa kit - CRISPR gene activation of mouse FXYD domain-containing ion transport regulator 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Fxyd1
• Locus ID: 56188
• Kit Components:

  GA205849G1, Fxyd1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA205849G2, Fxyd1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA205849G3, Fxyd1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_019503, NM_052991, NM_052992, NM_194321
• Synonyms: 0610012C17Rik; 1110006M24Rik; Plm; Pml
• Summary: This gene encodes a member of the FXYD family of small membrane proteins that share a 35-amino acid signature sequence domain, beginning with the sequence PFXYD and containing 7 invariant and 6 highly conserved amino acids. The protein encoded by this gene is a plasma membrane substrate for several kinases, including protein kinase A, protein kinase C, NIMA kinase, and myotonic dystrophy kinase. It is thought to form an ion channel or regulate ion channel activity and act as an accessory protein of Na,K-ATPase. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009]