Mouse Akap8 activation kit by CRISPRa

CAT#: GA205946

Akap8 CRISPRa kit - CRISPR gene activation of mouse A kinase (PRKA) anchor protein 8


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Akap8
Locus ID 56399
Kit Components

GA205946G1, Akap8 gRNA vector 1 in pCas-Guide-CRISPRa

GA205946G2, Akap8 gRNA vector 2 in pCas-Guide-CRISPRa

GA205946G3, Akap8 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_019774, NR_131218, NR_131219, NM_001357760
Synonyms 1200016A02Rik; AA673585; AKAP-8; AKAP95; AU015639
Summary This gene encodes a member of the A-kinase anchoring protein (AKAP) family. These proteins are characterized by their ability to bind to the R subunit of protein kinase A (PKA) and anchor the protein at different subcellular locations. This protein has been shown to regulate apoptosis and to be involved in palatogenesis. Knockdown of this gene has been associated with altered histone modifications and reduced expression of developmental genes in mouse embryonic stem cells. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Mar 2015]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.