Mouse Klk11 activation kit by CRISPRa

CAT#: GA206028

Klk11 CRISPRa kit - CRISPR gene activation of mouse kallikrein related-peptidase 11

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Klk11
• Locus ID: 56538
• Kit Components:

  GA206028G1, Klk11 gRNA vector 1 in pCas-Guide-CRISPRa

  GA206028G2, Klk11 gRNA vector 2 in pCas-Guide-CRISPRa

  GA206028G3, Klk11 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001177373, NM_019974
• Synonyms: 2310015I08Rik; Prss20; TLSP
• Summary: This gene encodes a member of the kallikrein subfamily of serine proteases that are involved in diverse physiological functions such as skin desquamation, tooth enamel formation, seminal liquefaction, synaptic neural plasticity and brain function. The encoded preproprotein undergoes proteolytic cleavage of the activation peptide to generate the functional enzyme. This gene is located in a cluster of several related kallikrein genes on chromosome 7. [provided by RefSeq, May 2016]