Mouse Rad18 activation kit by CRISPRa

CAT#: GA206255

Rad18 CRISPRa kit - CRISPR gene activation of mouse RAD18 E3 ubiquitin protein ligase

SDS

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Find the corresponding CRISPRi Inhibitor Kit

USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Rad18
Locus ID 58186
Kit Components

GA206255G1, Rad18 gRNA vector 1 in pCas-Guide-CRISPRa

GA206255G2, Rad18 gRNA vector 2 in pCas-Guide-CRISPRa

GA206255G3, Rad18 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058
Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001167730, NM_021385
Synonyms 2810024C04Rik; Rad18sc
Summary E3 ubiquitin-protein ligase involved in postreplication repair of UV-damaged DNA. Postreplication repair functions in gap-filling of a daughter strand on replication of damaged DNA. Associates to the E2 ubiquitin conjugating enzyme UBE2B to form the UBE2B-RAD18 ubiquitin ligase complex involved in mono-ubiquitination of DNA-associated PCNA on 'Lys-164'. Has ssDNA binding activity. [UniProtKB/Swiss-Prot Function]

Other Versions

SKU Description Size Price
KN514408 Rad18 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated.
    • 1 kit

USD 1,290.00

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.