Mouse Cysltr1 activation kit by CRISPRa
CAT#: GA206306
Cysltr1 CRISPRa kit - CRISPR gene activation of mouse cysteinyl leukotriene receptor 1
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | Cysltr1 |
Locus ID | 58861 |
Kit Components | GA206306G1, Cysltr1 gRNA vector 1 in pCas-Guide-CRISPRa GA206306G2, Cysltr1 gRNA vector 2 in pCas-Guide-CRISPRa GA206306G3, Cysltr1 gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001281859, NM_001281862, NM_021476 |
Synonyms | BB147369; Cyslt1; CysLT1R |
Summary | Receptor for cysteinyl leukotrienes mediating constriction of the microvascular smooth muscle during an inflammatory response. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The rank order of affinities for the leukotrienes is LTD4 >> LTE4 = LTC4 >> LTB4. [UniProtKB/Swiss-Prot Function] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN504200 | Cysltr1 - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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