Mouse Bco1 activation kit by CRISPRa

CAT#: GA206414

Bco1 CRISPRa kit - CRISPR gene activation of mouse beta-carotene oxygenase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Bco1
• Locus ID: 63857
• Kit Components:

  GA206414G1, Bco1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA206414G2, Bco1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA206414G3, Bco1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001163028, NM_021486
• Synonyms: Bcdo; Bcdo1; Bcmo1; beta-CD; betaCMOOX; CMO1; Cmoi
• Summary: Vitamin A metabolism is important for vital processes such as vision, embryonic development, cell differentiation, and membrane and skin protection. The protein encoded by this gene is a key enzyme in beta-carotene metabolism to vitamin A. It catalyzes the oxidative cleavage of beta,beta-carotene into two retinal molecules. Two alternatively spliced variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2009]