Mouse Ctsz activation kit by CRISPRa

CAT#: GA206439

Ctsz CRISPRa kit - CRISPR gene activation of mouse cathepsin Z

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Ctsz
• Locus ID: 64138
• Kit Components:

  GA206439G1, Ctsz gRNA vector 1 in pCas-Guide-CRISPRa

  GA206439G2, Ctsz gRNA vector 2 in pCas-Guide-CRISPRa

  GA206439G3, Ctsz gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022325
• Synonyms: AI787083; AU019819; CTSX; D2Wsu143e
• Summary: This gene encodes a member of the peptidase C1 (papain) family of cysteine proteases. The encoded preproprotein is proteolytically processed to generate a mature enzyme with carboxypeptidase activity. An enzymatically inactive form of the protein, that is associated with the propeptide, may be involved in cancer cell invasion and proliferation. Homozygous knockout mice for this gene exhibit impaired cancer cell invasion in a breast cancer model. [provided by RefSeq, Aug 2015]