Mouse Fgf23 activation kit by CRISPRa

CAT#: GA206480

Fgf23 CRISPRa kit - CRISPR gene activation of mouse fibroblast growth factor 23

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Fgf23
• Locus ID: 64654
• Kit Components:

  GA206480G1, Fgf23 gRNA vector 1 in pCas-Guide-CRISPRa

  GA206480G2, Fgf23 gRNA vector 2 in pCas-Guide-CRISPRa

  GA206480G3, Fgf23 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_022657
• Summary: This gene encodes a member of the fibroblast growth factor family. The encoded protein regulates phosphate homeostasis and vitamin D metabolism. Mutation of the related gene in humans causes autosomal dominant hypophosphatemic rickets (ADHR). The secreted protein is further cleaved into N- and C-terminal chains, which results in loss of function. [provided by RefSeq, Mar 2013]