Mouse Dzip1 activation kit by CRISPRa

CAT#: GA206846

Dzip1 CRISPRa kit - CRISPR gene activation of mouse DAZ interacting protein 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dzip1
• Locus ID: 66573
• Kit Components:

  GA206846G1, Dzip1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA206846G2, Dzip1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA206846G3, Dzip1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025943, NR_130725, NM_001360411, NM_001360412, NM_001360413
• Synonyms: 2510025K24Rik; 2810422M04Rik
• Summary: This gene encodes a zinc finger protein that has been demonstrated to interact with the deleted in azoospermia (DAZ) protein. DAZ plays an important role early in germ cell development to maintain the initial germ cell population. Deletion of this gene in mice compromises Hedgehog signaling during embryogenesis. Mouse embryos lacking the encoded protein show severe developmental defects with dorsalized neural tubes and underdeveloped somites. Alternative splicing of this gene results in multiple transcript variants. A pseudogene for this gene has been identified on chromosome 5. [provided by RefSeq, Jan 2015]