Mouse Dynlt3 activation kit by CRISPRa

CAT#: GA207147

Dynlt3 CRISPRa kit - CRISPR gene activation of mouse dynein light chain Tctex-type 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dynlt3
• Locus ID: 67117
• Kit Components:

  GA207147G1, Dynlt3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA207147G2, Dynlt3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA207147G3, Dynlt3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_025975
• Synonyms: 2310075M16Rik; AU042796; Tcte1l
• Summary: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. Probably binds BUB3 as part of transport cargo. Required for the efficient progression through mitosis. [UniProtKB/Swiss-Prot Function]