Mouse Dcxr activation kit by CRISPRa

CAT#: GA207565

Dcxr CRISPRa kit - CRISPR gene activation of mouse dicarbonyl L-xylulose reductase

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dcxr
• Locus ID: 67880
• Kit Components:

  GA207565G1, Dcxr gRNA vector 1 in pCas-Guide-CRISPRa

  GA207565G2, Dcxr gRNA vector 2 in pCas-Guide-CRISPRa

  GA207565G3, Dcxr gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001347608, NM_026428
• Synonyms: 0610038K04Rik; 1810027P18Rik; XR
• Summary: Catalyzes the NADPH-dependent reduction of several pentoses, tetroses, trioses, alpha-dicarbonyl compounds and L-xylulose. Participates in the uronate cycle of glucose metabolism. May play a role in the water absorption and cellular osmoregulation in the proximal renal tubules by producing xylitol, an osmolyte, thereby preventing osmolytic stress from occurring in the renal tubules. [UniProtKB/Swiss-Prot Function]