Mouse Trim37 activation kit by CRISPRa

CAT#: GA207909

Trim37 CRISPRa kit - CRISPR gene activation of mouse tripartite motif-containing 37

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Trim37
• Locus ID: 68729
• Kit Components:

  GA207909G1, Trim37 gRNA vector 1 in pCas-Guide-CRISPRa

  GA207909G2, Trim37 gRNA vector 2 in pCas-Guide-CRISPRa

  GA207909G3, Trim37 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_197987, NM_001363025, NM_001363026, NM_001363027, NM_001363028
• Synonyms: 1110032A10Rik; 2810004E07Rik; AI848587; AU043018; mKIAA0898; MUL; TEF3
• Summary: The protein encoded by this gene is part of the tripartite-motif containing family (TRIM), which is typified by the RING, B-box type 1, B-box type 2, and coiled-coil region domains. In mouse this protein is proposed to oligomerize through its coiled coil domain and has been reported to be expressed in neural crest-derived tissues as well as in tissues whose development is regulated by mesenchymal-epithelial interactions. In humans, mutations in this gene are associated with mulibrey (muscle-liver-brain-eye) nanism, an autosomal recessive disorder characterized by prenatal onset growth failure, cardiomyopathy and dysmorphic features. [provided by RefSeq, Jan 2013]