Mouse Cpvl activation kit by CRISPRa

CAT#: GA208787

Cpvl CRISPRa kit - CRISPR gene activation of mouse carboxypeptidase, vitellogenic-like

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Cpvl
• Locus ID: 71287
• Kit Components:

  GA208787G1, Cpvl gRNA vector 1 in pCas-Guide-CRISPRa

  GA208787G2, Cpvl gRNA vector 2 in pCas-Guide-CRISPRa

  GA208787G3, Cpvl gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001289713, NM_001289714, NM_027749
• Synonyms: 4933436L16Rik; HVLP
• Summary: This gene encodes a member of the serine carboxypeptidase family of proteases that cleave amino acids from the C-terminus of a protein substrate. The human ortholog of this gene, where it was first characterized, was found to be upregulated during the maturation of monocytes to macrophages. The encoded protein may be involved in antigen processing, digestion of phagocytosed proteins in the lysosome and lamellipodium formation. Disruption of this gene in mice was found to cause embryonic lethality. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Aug 2015]