Mouse Adipor1 activation kit by CRISPRa

CAT#: GA209311

Adipor1 CRISPRa kit - CRISPR gene activation of mouse adiponectin receptor 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adipor1
• Locus ID: 72674
• Kit Components:

  GA209311G1, Adipor1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA209311G2, Adipor1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA209311G3, Adipor1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001306069, NM_028320
• Synonyms: 2810031L11Rik; ACDCR1; CGI-45; Paqr1
• Summary: This gene encodes a receptor for the fat-derived hormone adiponectin. Binding of adiponectin to the encoded protein results in activation of an AMP-activated kinase signaling pathway which affects levels of fatty acid oxidation and insulin sensitivity. Homozygous knockout mice for this gene exhibit elevated plasma glucose and insulin levels as well as impaired glucose tolerance. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]