Mouse Whrn activation kit by CRISPRa

CAT#: GA209601

Whrn CRISPRa kit - CRISPR gene activation of mouse whirlin

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Whrn
• Locus ID: 73750
• Kit Components:

  GA209601G1, Whrn gRNA vector 1 in pCas-Guide-CRISPRa

  GA209601G2, Whrn gRNA vector 2 in pCas-Guide-CRISPRa

  GA209601G3, Whrn gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001008791, NM_001008792, NM_001008793, NM_001008794, NM_001008795, NM_001008796, NM_001008797, NM_001008798, NM_001276371, NM_028640
• Synonyms: 1110035G07Rik; AW122018; AW742671; C430046P22Rik; Dfnb31; Ush2d; wi
• Summary: This gene encodes a protein required for elongation and actin polymerization in the hair cell stereocilia. The encoded protein is localized to the cytoplasm and co-localizes with the growing end of actin filaments. Mutations in this gene have been linked to deafness. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2013]