Mouse Dmgdh activation kit by CRISPRa

CAT#: GA209733

Dmgdh CRISPRa kit - CRISPR gene activation of mouse dimethylglycine dehydrogenase precursor

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Dmgdh
• Locus ID: 74129
• Kit Components:

  GA209733G1, Dmgdh gRNA vector 1 in pCas-Guide-CRISPRa

  GA209733G2, Dmgdh gRNA vector 2 in pCas-Guide-CRISPRa

  GA209733G3, Dmgdh gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_028772
• Synonyms: 1200014D15Rik; AI787269
• Summary: This gene encodes an enzyme involved in the catabolism of choline, catalyzing the oxidative demethylation of dimethylglycine to form sarcosine. The enzyme is found as a monomer in the mitochondrial matrix, and uses flavin adenine dinucleotide and folate as cofactors. [provided by RefSeq, Jul 2013]