Mouse Gpx6 activation kit by CRISPRa

CAT#: GA210242

Gpx6 CRISPRa kit - CRISPR gene activation of mouse glutathione peroxidase 6

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Gpx6
• Locus ID: 75512
• Kit Components:

  GA210242G1, Gpx6 gRNA vector 1 in pCas-Guide-CRISPRa

  GA210242G2, Gpx6 gRNA vector 2 in pCas-Guide-CRISPRa

  GA210242G3, Gpx6 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145451
• Synonyms: 1700020G18Rik; olfactory; Ry2d1
• Summary: This gene encodes a member of the glutathione peroxidase family. Glutathione peroxidases catalyze the reduction of a variety of hydroperoxides using glutathione as a specific electron donor substrate, and thereby protect cells against oxidative damage. Expression of this gene is restricted to embryos and adult olfactory epithelium. The mouse and rat orthologs contain a cysteine (Cys) residue at the active site, unlike the human counterpart, which is a selenoprotein, containing selenocysteine (Sec) instead. [provided by RefSeq, Jul 2017]