Mouse Creb3l4 activation kit by CRISPRa

CAT#: GA210930

Creb3l4 CRISPRa kit - CRISPR gene activation of mouse cAMP responsive element binding protein 3-like 4

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Creb3l4
• Locus ID: 78284
• Kit Components:

  GA210930G1, Creb3l4 gRNA vector 1 in pCas-Guide-CRISPRa

  GA210930G2, Creb3l4 gRNA vector 2 in pCas-Guide-CRISPRa

  GA210930G3, Creb3l4 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001307934, NM_001307935, NM_030080
• Synonyms: 1700012K17Rik; 5330432F22Rik; acre1; AIBZIP; AV040530; AV258827; CREB4; JAL; TISP40
• Summary: This gene encodes a CREB (cyclic AMP-responsive element-binding) protein with a transmembrane domain which localizes it to the ER membrane. The encoded protein may play a role in adiposity and male germ cell development. Homozygous knockout mice for this gene show increased adipogenesis, elevated testicular germ cell apoptosis and defects in spermatogenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Apr 2015]