Mouse Fgg activation kit by CRISPRa

CAT#: GA211558

Fgg CRISPRa kit - CRISPR gene activation of mouse fibrinogen gamma chain

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Fgg
• Locus ID: 99571
• Kit Components:

  GA211558G1, Fgg gRNA vector 1 in pCas-Guide-CRISPRa

  GA211558G2, Fgg gRNA vector 2 in pCas-Guide-CRISPRa

  GA211558G3, Fgg gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001317105, NM_133862
• Synonyms: 3010002H13Rik; AI256424
• Summary: This gene encodes the gamma subunit of the coagulation factor fibrinogen, which is a component of the blood clot. Mice lacking the encoded protein did not possess detectable amounts of plasma fibrinogen. Pregnant mice lacking the encoded protein die due to heavy bleeding during delivery. This gene is located adjacent to the genes encoding fibrinogen alpha and gamma subunits on chromosome 3. Alternate splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Nov 2015]