Mouse Npy activation kit by CRISPRa

CAT#: GA212238

Npy CRISPRa kit - CRISPR gene activation of mouse neuropeptide Y

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Npy
• Locus ID: 109648
• Kit Components:

  GA212238G1, Npy gRNA vector 1 in pCas-Guide-CRISPRa

  GA212238G2, Npy gRNA vector 2 in pCas-Guide-CRISPRa

  GA212238G3, Npy gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_023456
• Synonyms: 0710005A05Rik
• Summary: This gene encodes a neuropeptide that plays a pivotal role in many physiological functions such as food intake, energy homeostasis, circadian rhythm, and cognition. The encoded protein precursor undergoes proteolytic processing to generate the biologically active peptide. Mice lacking the encoded protein exhibit mild seizures occasionally and become hyperphagic following food deprivation. A deficiency of the encoded protein partially prevents mice lacking leptin from becoming obese. [provided by RefSeq, Oct 2015]