Mouse Adam33 activation kit by CRISPRa

CAT#: GA212338

Adam33 CRISPRa kit - CRISPR gene activation of mouse a disintegrin and metallopeptidase domain 33

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adam33
• Locus ID: 110751
• Kit Components:

  GA212338G1, Adam33 gRNA vector 1 in pCas-Guide-CRISPRa

  GA212338G2, Adam33 gRNA vector 2 in pCas-Guide-CRISPRa

  GA212338G3, Adam33 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001163529, NM_033615, NR_136922
• Synonyms: Adaml
• Summary: This gene encodes a member of a disintegrin and metalloprotease (ADAM) family of endoproteases that play important roles in various biological processes including cell signaling, adhesion and migration. This gene is widely expressed, most highly in the adult brain, heart, kidney, lung and testis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional metalloprotease enzyme. Alternative splicing results in multiple transcript variants encoding different isoforms, some of which may undergo similar processing. [provided by RefSeq, May 2016]