Mouse Bsnd activation kit by CRISPRa

CAT#: GA212500

Bsnd CRISPRa kit - CRISPR gene activation of mouse barttin CLCNK type accessory beta subunit

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Bsnd
• Locus ID: 140475
• Kit Components:

  GA212500G1, Bsnd gRNA vector 1 in pCas-Guide-CRISPRa

  GA212500G2, Bsnd gRNA vector 2 in pCas-Guide-CRISPRa

  GA212500G3, Bsnd gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_080458
• Synonyms: MGC47291
• Summary: Functions as a beta-subunit for CLCNKA and CLCNKB chloride channels. In the kidney CLCNK/BSND heteromers mediate chloride reabsorption by facilitating its basolateral efflux. In the stria, CLCNK/BSND channels drive potassium secretion by recycling chloride for the basolateral SLC12A2 cotransporter. [UniProtKB/Swiss-Prot Function]