Mouse Khdrbs2 activation kit by CRISPRa

CAT#: GA212609

Khdrbs2 CRISPRa kit - CRISPR gene activation of mouse KH domain containing, RNA binding, signal transduction associated 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Khdrbs2
• Locus ID: 170771
• Kit Components:

  GA212609G1, Khdrbs2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA212609G2, Khdrbs2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA212609G3, Khdrbs2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_133235
• Synonyms: 6330586C16Rik; mSLM-1; Slim1; Slm-1; Slm1
• Summary: The protein encoded by this gene is similar to the src associated in mitosis, 68 kDa protein, which is an RNA-binding protein and a substrate for Src-family tyrosine kinases during mitosis. This protein has a KH RNA-binding motif and proline-rich motifs which may be SH2 and SH3 domain binding sites. A similar rat protein is an RNA-binding protein which is tyrosine phosphorylated by Src during mitosis. These studies also suggest that the rat protein may function as an adaptor protein for Src by binding the SH2 and SH3 domains of various other proteins. [provided by RefSeq, Jul 2008]