Mouse Ripk2 activation kit by CRISPRa

CAT#: GA212726

Ripk2 CRISPRa kit - CRISPR gene activation of mouse receptor (TNFRSF)-interacting serine-threonine kinase 2


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USD 1,290.00

2 Weeks*

Size
    • 1 kit

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Specifications

Product Data
Format 3gRNAs, 1 scramble ctrl and 1 enhancer vector
Symbol Ripk2
Locus ID 192656
Kit Components

GA212726G1, Ripk2 gRNA vector 1 in pCas-Guide-CRISPRa

GA212726G2, Ripk2 gRNA vector 2 in pCas-Guide-CRISPRa

GA212726G3, Ripk2 gRNA vector 3 in pCas-Guide-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100058

Disclaimer The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq NM_001329751, NM_138952, NR_138102
Synonyms 2210420D18Rik; CARD3; CARDIAK; CCK; D4Bwg0615e; RICK; RIP2
Summary This gene encodes a member of the receptor-interacting protein family of serine/threonine protein kinases. The encoded protein contains a C-terminal caspase activation and recruitment domain, and is a component of signaling complexes in both the innate and adaptive immune pathways. It is a potent activator of nuclear factor kappa B and inducer of apoptosis in response to various stimuli. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Jul 2016]

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*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.