Mouse Eif2b1 activation kit by CRISPRa

CAT#: GA212927

Eif2b1 CRISPRa kit - CRISPR gene activation of mouse eukaryotic translation initiation factor 2B, subunit 1 (alpha)

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Eif2b1
• Locus ID: 209354
• Kit Components:

  GA212927G1, Eif2b1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA212927G2, Eif2b1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA212927G3, Eif2b1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_145371
• Synonyms: D5Ertd406e; EIF2BA
• Summary: This gene encodes the alpha subunit of the eukaryotic translation initiation factor complex 2B (eIF2B). The eIF2B complex is a heterodecamer comprised of two molecules each of alpha, beta, gamma, delta and epsilon subunits. The eIF2B complex is a critical regulator of protein synthesis acting as the guanine nucleotide exchange factor for eIF2 to enable the formation of ternary complex that is required for the initiation of mRNA translation. [provided by RefSeq, Aug 2015]