Mouse Agap2 activation kit by CRISPRa

CAT#: GA213349

Agap2 CRISPRa kit - CRISPR gene activation of mouse ArfGAP with GTPase domain, ankyrin repeat and PH domain 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Agap2
• Locus ID: 216439
• Kit Components:

  GA213349G1, Agap2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA213349G2, Agap2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA213349G3, Agap2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001033263, NM_001301014
• Synonyms: AGAP-2; Centg1; cnt-g1; mKIAA0167; PIKE
• Summary: The protein encoded by this gene is a member of the centaurin GTPase family. This gene product regulates the activity of multiple kinases, including PI3K. Reduced expression of this gene results in multiple defects, including neural deficiencies, while increased expression of this gene has been observed in some tumors. Alternative splicing results in multiple protein isoforms. [provided by RefSeq, Jul 2014]