Mouse Adm2 activation kit by CRISPRa

CAT#: GA213644

Adm2 CRISPRa kit - CRISPR gene activation of mouse adrenomedullin 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Adm2
• Locus ID: 223780
• Kit Components:

  GA213644G1, Adm2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA213644G2, Adm2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA213644G3, Adm2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_182928
• Synonyms: Am2; IMD; Imdn
• Summary: This gene encodes a member of the calcitonin gene-related peptide (CGRP)/calcitonin family of hormones that play a role in the regulation of cardiovascular homeostasis, prolactin release, anti-diuresis, anti-natriuresis, and regulation of food and water intake. The encoded protein is proteolytically processed to generate one or more biologically active peptides. Intravenous injection of the active peptide was found to protect mouse lungs from ischemia/reperfusion injury. [provided by RefSeq, Aug 2015]