Mouse Usp1 activation kit by CRISPRa

CAT#: GA214153

Usp1 CRISPRa kit - CRISPR gene activation of mouse ubiquitin specific peptidase 1

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Usp1
• Locus ID: 230484
• Kit Components:

  GA214153G1, Usp1 gRNA vector 1 in pCas-Guide-CRISPRa

  GA214153G2, Usp1 gRNA vector 2 in pCas-Guide-CRISPRa

  GA214153G3, Usp1 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001301414, NM_146144, NM_001356424
• Summary: This gene encodes a member of the ubiquitin-specific peptidase family. The encoded protein acts as a catalytic subunit in a heterodimeric deubiquitinating enzyme complex that deubiquitinates Fanconi anemia, complementation group D2, and plays a role in homologous recombination-mediated DNA repair. Disruption of this gene is associated with a Fanconi anemia-like phenotype and genomic instability. Alternative splicing results in multiple transcript variants. Pseudogenes of this gene have been defined on chromosomes 3, 12, and 15. [provided by RefSeq, Aug 2014]