Mouse C8a activation kit by CRISPRa
CAT#: GA214154
C8a CRISPRa kit - CRISPR gene activation of mouse complement component 8, alpha polypeptide
Find the corresponding CRISPRi Inhibitor Kit
USD 1,290.00
2 Weeks*
Specifications
Product Data | |
Format | 3gRNAs, 1 scramble ctrl and 1 enhancer vector |
Symbol | C8a |
Locus ID | 230558 |
Kit Components | GA214154G1, C8a gRNA vector 1 in pCas-Guide-CRISPRa GA214154G2, C8a gRNA vector 2 in pCas-Guide-CRISPRa GA214154G3, C8a gRNA vector 3 in pCas-Guide-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100058 |
Disclaimer | The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_001290645, NM_001316667, NM_146148 |
Summary | This gene encodes the alpha subunit of complement component C8 that participates in the assembly of the complement membrane attack complex. The encoded preproprotein undergoes proteolytic processing to generate the alpha subunit, which associates with the beta and gamma subunits to form a trimeric complement component, C8. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. This gene is located adjacent to the gene encoding the beta subunit. [provided by RefSeq, Oct 2015] |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN502394 | C8a - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
USD 1,290.00 |
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