Mouse Agfg2 activation kit by CRISPRa

CAT#: GA214292

Agfg2 CRISPRa kit - CRISPR gene activation of mouse ArfGAP with FG repeats 2

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Agfg2
• Locus ID: 231801
• Kit Components:

  GA214292G1, Agfg2 gRNA vector 1 in pCas-Guide-CRISPRa

  GA214292G2, Agfg2 gRNA vector 2 in pCas-Guide-CRISPRa

  GA214292G3, Agfg2 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001303266, NM_001303271, NM_145566, NM_178162
• Synonyms: A630095P14Rik; Hrbl; RAB-R; RABR
• Summary: This gene encodes a paralog of the HIV-1 Rev binding proteins that serve as cellular co-factors for HIV-1 Rev protein in shuttling viral pre-mRNAs from the nucleus to the cytoplasm. The encoded protein contains an ADP-ribosylation factor GTPase activating protein (Arf-GAP) zinc finger domain, several phenylalanine-glycine (FG) motifs and asparagine-proline-phenylalanine (NPF) motifs. Alternate splicing of this gene results in multiple transcript variants. [provided by RefSeq, Dec 2014]