Mouse Nsd3 activation kit by CRISPRa

CAT#: GA214510

Nsd3 CRISPRa kit - CRISPR gene activation of mouse nuclear receptor binding SET domain protein 3

Product Images

Specifications

Product Data

• Format: 3gRNAs, 1 scramble ctrl and 1 enhancer vector
• Symbol: Nsd3
• Locus ID: 234135
• Kit Components:

  GA214510G1, Nsd3 gRNA vector 1 in pCas-Guide-CRISPRa

  GA214510G2, Nsd3 gRNA vector 2 in pCas-Guide-CRISPRa

  GA214510G3, Nsd3 gRNA vector 3 in pCas-Guide-CRISPRa

  1 CRISPRa-Enhancer vector, SKU GE100056

  1 CRISPRa scramble vector, SKU GE100058

• Disclaimer: The kit is designed based on the best knowledge of CRISPa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.

Reference Data

• RefSeq: NM_001001735, NM_001081269, NM_001308481, NM_001308482
• Synonyms: 6720429E03; A530023P05; AI528490; WHISTLE; Whsc1l1
• Summary: This gene encodes a member of the SET domain family of histone lysine N-methyltransferase proteins. This protein methylates histone H3 at lysine residues 4 and 27, which represses gene transcription. It acts in opposition to the histone demethylase Jmjd1c. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2015]